Ayden Benjamin

  • Retinoids (vitamin A) are important for a number of physiological and developmental processes including reproduction. Retinoic acid, one of the retinoids, plays an essential role in early development and maintenance of specific tissue types. Khillan and colleagues demonstrated that retinol can be used to maintain mESCs in a pluripotent state in…[Read more]

  • Cities across Europe are already experiencing an increase in ZIKV importations via travellers from the Americas (Maria et al., 2016; Zammarchi et al., 2015). Two recent studies assessed the risk of transmission of ZIKV in Europe reaching contrasting conclusions (Guzzetta et al., 2016; WHO, 2016). One of the studies finds minimal risk based on an…[Read more]

  • The objective was to understand the neuraminidase inhibitor of this organism across Europe and to get insight into the geographical and temporal evolution of the different genotypes. The diversity of P. jirovecii isolates responsible for PCP across different European countries (n=12) was investigated, in order to detect the most prevalent…[Read more]

  • Ayden Benjamin posted an update 2 weeks ago

    The last century has witnessed incredible progresses in the control of infectious diseases. However, respiratory pathogens continue to threaten humans and cause serious public health and economic problems. Not only emerging pathogens but also viruses that have been known for a while continue to cause widespread issues (). Despite the relative…[Read more]

  • Ayden Benjamin posted an update 2 weeks ago

    IntroductionAdvances in single nucleotide polymorphism (SNP) array technologies and Next Generation Sequencing have made it practical to perform Genome-Wide Association Studies (GWAS), an unbiased genomic approach to identify genetic factors that account for cancer susceptibility. Following initial GWAS (Zheng et al., 2009; Turnbull et al., 2010),…[Read more]

  • IntroductionSomatic Histone Compound Library can be reprogrammed into induced pluripotent stem cells (iPSCs) by the transduction of four embryonic transcriptional factors (Takahashi et al., 2007b; Takahashi and Yamanaka, 2006; Yu et al., 2007). This discovery provides not only a novel opportunity for regenerative medicine but also innovative cell…[Read more]

  • IntroductionThe ardent passion towards contributing to the society in order to save human lives was the main reason behind the origin of this project. Various articles which stated the numerous cessations of human lives while attempting to treat underground sewers intrigued our team to develop the model. [1,2] For those who work in atmospheres…[Read more]

  • ¿Qué buscaba lograr la Comisión de Cambios con las subastas de dólares? Al observar la distribución de los precios en los diferentes paneles de la Gráfica 3, así como los estadísticos del Cuadro 1, se establece la siguiente conjetura, el objetivo de la política cambiaria que se siguió durante el periodo de estudio (8 de diciembre de 2014 suppor…[Read more]

  • Planarians are a particularly well-suited animal model for the study of neoblast function, given the remarkable enrichment of this cell type in these animals (Reddien, 2013). Here, we showed that phagocyte depletion had no impact on instructed immunity. Instead, we found evidence of a critical role of neoblasts in instructed immunity. In support…[Read more]

  • As these pathogenic pathways are probably not specific for HIV infection but relevant to any situation of chronic immune activation, including aging, and given the frequency of these comorbidities, these observations are of general interest. It is for instance striking that HIV infection and the autoimmune disease rheumatoid arthritis share many…[Read more]

  • Main TextJust 10 years since the development of human induced pluripotent stem cell (hiPSC) technology (Takahashi et al., 2007), the use of these cells to model urokinase disorders and obtain disease-relevant information is becoming a tangible reality. Not only are we now able to better detect relevant genetic changes in a patient’s cells us…[Read more]

  • Ayden Benjamin posted an update 4 weeks ago

    To help define the chicken ES cells and PGC better, it would be advantageous to study the expression profiles of various genes related to pluripotency and to the germ cell identity, as has been done in mammalian cells (see Pashai et al., 2012). Here we report a comparative microarray analysis using various chicken stem cells. We define a molecular…[Read more]

  • Ayden Benjamin posted an update 4 weeks ago

    The fact that health outcomes did not improve across the board allows us to rule out with some confidence one type of spurious relationship impossible to control for within our model: neighborhood gentrification. Over the time aconitine of our study, if higher income households replace lower income households within the same neighborhood, we…[Read more]

  • Ayden Benjamin posted an update 1 month ago

    We used the VP64 transactivation domain to generate dTF activators. VP64 at the Oct4 distal enhancer would presumably recruit and interact with histone acetyltransferase p300 and transcriptional activation complexes (Ito et al., 2000; Milbradt et al., 2011) and induce epigenetic changes that facilitate binding of additional factors such as OCT4 i…[Read more]

  • Triglycerides play a central role in the regulation of lipoprotein interactions to maintain lipid metabolism. These lipids are not directly atherogenic but represent an important marker of atherosclerosis risk [24]. The elevated plasma triglyceride concentrations have been also associated with cholesterol esterification and very atherogenic LDL…[Read more]

  • Ola financiera UNAMMomento Económico UNAMArturo Huerta González, Otra vez el nulo crecimiento y César Armando Salazar, La economía mexicana: entre choques externos y la debilidad del mercado interno; en conjunto nos muestran las perspectivas de crecimiento para la economía mexicana al finalizar el 2015. Así como las circunstancias de la econo…[Read more]

  • Conflicts of interestIntroductionThe goal of islet transplantation is to use the donor β-cells to restore the insulin production and glycemic regulation in patients with type 1 diabetes to avoid serious complications (Barton et al., 2012; Goland and Egli, 2014). For long-term graft survival, neurovascular regeneration in the new islet…[Read more]

  • Are there unique learning opportunities during adolescence?Alongside the relatively bleak picture of a period where preexisting vulnerabilities find expression, it may also be the case that the adolescent-typical neurodevelopmental changes we have described enhance plasticity to positive environmental experiences (see Fig. 1). These experiences…[Read more]

  • Similar lesions may occur in varicella zoster virus infection. However, the pathogenesis of either herpes vegetans or verrucous zoster lesions remains undetermined. It has been suggested that the epidermal hyperplasia is due to cytokine release in relation to long-term infection. A genetic predisposition to the development of hypertrophic lesions…[Read more]

  • The analysis shows that room C requires approximately 1.9 times its current total power of prostaglandin receptor at low frequencies or 2.2 times at mid and high frequencies, whereas room RAZ requires approximately 1.6 times its current total power of absorption at low frequencies and 1.7 times at mid and high frequencies. To improve the…[Read more]

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